Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor transplantation: the analysis on behalf of the transplant complications working party of the EBMT – New Study
Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor transplantation: the analysis on behalf of the transplant complications working party of the EBMT
Summary
A study by the EBMT’s Transplant Complications Working Party analyzed outcomes of using post-transplantation cyclophosphamide (PTCy) and antithymocyte globulin (ATG) in HLA-mismatched unrelated donor transplants. Examining 8/10 HLA-mismatched transplants, the research likely focused on the impact of this combined immunosuppression strategy on graft-versus-host disease (GVHD), graft failure, and overall survival. Understanding the efficacy and safety profile of PTCy and ATG in this high-risk transplant setting is crucial for optimizing donor selection and immunosuppressive regimens to improve patient outcomes.
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