Immune checkpoint inhibitors (ICIs) are a type of immunotherapy or cancer treatment that targets specific immune cells known as T cells, which are responsi



Summary

Immune checkpoint inhibitors (ICIs) are a form of immunotherapy that targets T cells, the immune system’s primary defense against cancer. ICIs work by blocking proteins on T cells or cancer cells that prevent the immune system from attacking the tumor. By blocking these “checkpoints,” ICIs unleash the T cells’ ability to recognize and destroy cancer cells, leading to tumor regression. This approach has revolutionized cancer treatment, offering durable responses in various cancers, but can also cause immune-related side effects due to overstimulation of the immune system.

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