RNA could have helped amino acids join up without preexisting protein machinery, lab study suggests



Summary

A new lab study proposes that RNA may have played a crucial role in the formation of early life by enabling amino acids to bond without the presence of protein enzymes. Researchers found that RNA molecules, specifically those containing specific chemical modifications, could catalyze the formation of peptide bonds, the building blocks of proteins. This discovery supports the “RNA world” hypothesis, suggesting RNA was the primary genetic material and enzymatic catalyst before the evolution of DNA and proteins. This challenges the notion that complex protein machinery was necessary for early peptide formation.

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