Researchers from MIT have incorporated several modifications to prime editing systems, making them up to 60 times more precise.



Summary

MIT researchers have significantly improved the precision of prime editing, a gene-editing technology. By implementing multiple modifications to existing prime editing systems, they achieved up to a 60-fold increase in accuracy. This advancement minimizes unintended edits at off-target locations, a major concern in gene editing. The improved precision makes prime editing a more promising and safer tool for future therapeutic applications, enhancing its potential for treating genetic diseases. The specific modifications were not detailed in this summarized context.

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