A new study from Aarhus University shows that our cells’ ability to clean out old protein clumps, known as aggregates, also includes a—up till now unknown—partnership with an engine that breaks down bigger pieces into smaller before “taking it to the trash.” An important find for future treatments of diseases like Alzheimer’s, Parkinson’s, ALS and Huntington’s, which are all characterized by the accumulation of protein in the brain.



Summary

Aarhus University researchers discovered a new cellular cleanup process involving protein aggregate removal. The study reveals a partnership where an engine breaks down large protein clumps into smaller, manageable pieces before they are discarded. This previously unknown mechanism is crucial for understanding how cells maintain protein quality. The finding is significant for developing future treatments for neurodegenerative diseases like Alzheimer’s, Parkinson’s, ALS, and Huntington’s, all of which are linked to protein accumulation in the brain. This new insight could pave the way for therapies that enhance the cell’s ability to clear harmful protein aggregates.

Read more…

This post is part of “Science and Technology News”, Follow for more…!!!

Credits: Source

Disclaimer