Carboxylic acids are ubiquitous in bioactive organic molecules and readily available chemical building blocks. Carboxylic acids can be converted into carboxy radicals that can initiate versatile carbon–carbon and carbon–heteroatom bond formations, which are highly desirable for developing materials and pharmaceuticals. Currently, however, there are few applicable methods that use inexpensive catalysts.



Summary

Carboxylic acids are essential components in organic molecules and versatile in chemical synthesis. Their conversion to carboxy radicals allows for valuable carbon-carbon and carbon-heteroatom bond formations, crucial for creating new materials and pharmaceuticals. Despite the potential, current methods for this transformation are limited, particularly in their reliance on expensive catalysts. Developing inexpensive and efficient catalytic systems for converting carboxylic acids into carboxy radicals would significantly advance organic synthesis and related fields.

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