The gut microbiota in cancer immunity and immunotherapy Summary The gut microbiota plays a crucial role in shaping both local and systemic immune responses, significantly impacting cancer development and response to immunotherapy. Specific bacterial species Read More
Tags :immunity
Education, Research & Positions
Anti-tumor immunity is boosted by loss of TGFβ-driven tissue residency
Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02224-5 Tumor-infiltrating CD8+ T cells acquire HOBIT expression and features of tissue-resident memory cells. This TGFβ-driven process is dispensable for tumor control by immune checkpoint Read More
Nature Reviews Immunology, Published online: 29 July 2025; doi:10.1038/s41577-025-01206-w Modification of the nucleotide pool is emerging as key to innate immunity in animals, plants and bacteria. This Review explains how immune pathways conserved Read More
Science, Volume 389, Issue 6758, July 2025. Summary Without specific articles or content listed for the described Science issue, I can only offer a generic summary. Science, Volume 389, Issue 6758, published in July 2025, likely presents a diverse collection of Read More
Education, Research & Positions
Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a
Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a p53-transduced dendritic cell vaccine Summary This research explores combining oncolytic viruses and p53-enhanced dendritic cell (DC) vaccines to improve cancer immunotherapy. Specifically, DCs Read More
Education, Research & Positions
Microbiota-driven antitumour immunity mediated by dendritic cell migration – New
Microbiota-driven antitumour immunity mediated by dendritic cell migration Summary The gut microbiota plays a crucial role in shaping anti-tumor immunity. Specific gut bacteria stimulate the migration of dendritic cells (DCs) from the gut to tumor Read More
Education, Research & Positions
Targeting gut microbiota and arginase boosts MEK inhibitors’ enhancement of
Targeting gut microbiota and arginase boosts MEK inhibitors’ enhancement of antitumour immunity via MHC-I upregulation in colorectal cancer Summary MEK inhibitors, while promising for colorectal cancer (CRC) treatment, often face limited efficacy. This study reveals Read More
Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up Summary A half-century’s worth of immunology research data has undergone rigorous verification, strengthening confidence in established findings Read More
Education, Research & Positions
Targeting mTORC2 in lung squamous cell carcinoma improves anti-tumor immunity
Targeting mTORC2 in lung squamous cell carcinoma improves anti-tumor immunity through the PSGL-1-VISTA axis Summary Targeting mTORC2 in lung squamous cell carcinoma (LUSC) enhances anti-tumor immunity by modulating the PSGL-1-VISTA pathway. Specifically, mTORC2 Read More
Education, Research & Positions
Illuminating microbial dark matter: Dietary alterations uncover microbial regulation of
Science, Volume 389, Issue 6755, Page 38-38, July 2025. Summary Without knowing the specific content of that particular issue and page of Science, I can only provide a general summary. This entry likely represents an editorial or short “Read More
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