A revolutionary artificial intelligence platform allows scientists to accurately identify critical predictive biomarkers for pancreatic cancer. Summary A new AI platform is transforming pancreatic cancer research by precisely identifying key predictive biomarkers. This technology analyzes Read More
Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results Summary The AMPLIFY-201 phase 1 trial evaluated a novel lymph node-targeted vaccine targeting the mKRAS mutation in patients with pancreatic and Read More
Humans and chimpanzees share a close evolutionary relationship, genetically linking us. As a result, the two species can pass on infection and disease to o Summary Due to their close genetic relationship, humans and chimpanzees Read More
For many cases of gastric (stomach) or gastroesophageal (GEJ) cancer, the standard treatment involves surgical removal of the malignant tissue, along with Summary Surgical removal is a cornerstone of treatment for many gastric and gastroesophageal (Read More
Defects in antigen processing and presentation: mechanisms, immune evasion and implications for cancer vaccine development Summary Defects in antigen processing and presentation (APP) mechanisms are critical for immune surveillance and cancer control. These defects, arising Read More
Individuals with cannabis use disorder (CUD) are over three times more likely to develop oral cancer within five years than those without the condition. Summary A recent study reveals a significant link between cannabis use Read More
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation Summary ULBP2 CAR-T cells show promise in improving gastric cancer immunotherapy by targeting and killing tumor cells and simultaneously disrupting the tumor microenvironment. The Read More
Nanotechnology for immuno-oncology Summary Nanotechnology offers promising solutions for immuno-oncology, enhancing cancer immunotherapy’s effectiveness. Nanoparticles can improve drug delivery to tumors and immune cells, overcoming limitations of traditional methods like poor solubility and systemic Read More
Since the invention of the first vaccine over two centuries ago, new discoveries have emerged to confer better protection. Summary For over two centuries, vaccines have been a crucial tool in combating disease. Starting with Read More
The gut microbiota in cancer immunity and immunotherapy Summary The gut microbiota plays a crucial role in shaping both local and systemic immune responses, significantly impacting cancer development and response to immunotherapy. Specific bacterial species Read More
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