Researchers have discovered that brain cancer cells reprogram their sugar metabolism, a vulnerability that can be exploited in mice to impede tumor growth and enhance therapeutic outcomes. Glioblastomas are the most aggressive type of malignant brain tumor, and patients diagnosed with this condition typically survive only one to two years. Within these tumors, ordinary brain […]



Summary

Glioblastoma, a deadly brain cancer, is being targeted through its altered sugar metabolism. Researchers found that these cancer cells reprogram their sugar usage, making them vulnerable. In mice, exploiting this vulnerability slowed tumor growth and improved therapy results. This discovery highlights a potential new strategy for fighting glioblastoma, which currently has a poor prognosis. Understanding this metabolic shift may lead to more effective treatments for this aggressive cancer.

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