In exclusive chat with Science, Loreen Willenberg describes remaining HIV-free even after immune-suppressing therapies for brain and lung tumors



Summary

Loreen Willenberg, a rare “elite controller” of HIV, maintains a naturally suppressed viral load without medication. Science magazine interviewed her about her unique ability. Even more remarkable, Willenberg remained HIV-free despite undergoing intensive chemotherapy and radiation treatments for brain and lung tumors. These treatments severely weakened her immune system, creating conditions where the virus would normally rebound. Her case provides valuable insight into the natural immune mechanisms that control HIV and could potentially guide future therapeutic strategies towards achieving viral remission in others. Her resilient HIV control even during immune suppression offers an extraordinary case study.

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