Nature Immunology, Published online: 21 July 2025; doi:10.1038/s41590-025-02229-0

Giardia intestinalis is a protozoan parasite that can cause severe enteric disease. The immune response to this organism provides unexpected benefits to limit gut inflammation.



Summary

A new study in Nature Immunology highlights the surprising role of the immune response to Giardia intestinalis in mitigating gut inflammation. While Giardia is a parasitic protozoan known for causing severe enteric disease, the research reveals that the body’s immune response to the parasite can actually offer protective effects against excessive inflammation in the gut. This unexpected finding sheds light on the complex interplay between parasites, the immune system, and gut health, suggesting potential new avenues for therapeutic intervention.

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