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Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses – New Study


Nature Reviews Immunology, Published online: 28 July 2025; doi:10.1038/s41577-025-01217-7

Exercise promotes changes in the gut microbiota that enhance anti-tumour T cell responses.



Summary

A Nature Reviews Immunology article (published July 28, 2025) highlights the connection between exercise and improved anti-tumor immunity. The review focuses on how physical activity alters the composition and function of the gut microbiota. These exercise-induced microbial shifts subsequently enhance the activity of T cells, immune cells critical for fighting cancer. The article suggests that exercise, by modulating the gut microbiome, can be a valuable tool in boosting the body’s natural defenses against tumors. This opens potential avenues for developing exercise-based interventions to improve cancer treatment outcomes.

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Dr AF Saeed

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