Nature Reviews Immunology, Published online: 24 July 2025; doi:10.1038/s41577-025-01203-z

This Review by Poirier highlights the intrinsic mechanisms that protect stem cells from infection. The author also explains how stem cell populations in different tissue sites respond to infection or injury to protect tissue integrity, and the impact of inflammageing on these processes.



Summary

Poirier’s Review in Nature Reviews Immunology (July 2025) explores the intrinsic defense mechanisms stem cells employ against infection. It elucidates how stem cells, varying by tissue location, react to infection or injury to maintain tissue integrity. The review specifically addresses the critical interplay between stem cell protection and tissue preservation amidst infectious challenges and physical damage. Finally, Poirier underscores the influence of “inflammageing,” the age-related chronic inflammation, on these protective stem cell processes, suggesting a crucial link between aging, immunity, and stem cell function.

Read more…

Credits: Source

This post is part of “Science/Immunology News”, Follow for more…!!!