Scientists have uncovered how rogue DNA rings may help spark glioblastoma at its earliest stages. An international research team has shown that rogue rings of DNA that exist outside chromosomes, called extrachromosomal DNA, or ecDNA, can drive the growth of many glioblastomas, the most common and most aggressive brain cancer in adults. The results point […]



Summary

Scientists discovered that extrachromosomal DNA (ecDNA), rogue rings of DNA outside chromosomes, plays a key role in the early development of glioblastoma, an aggressive brain cancer. This research highlights that ecDNA drives the growth of many glioblastomas. The finding is significant because it offers new insights into the origins of this deadly cancer and opens potential avenues for targeted therapies. By understanding how ecDNA contributes to tumor formation, researchers hope to develop strategies to disrupt this process and ultimately improve treatment outcomes for glioblastoma patients.

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