Education, Research & Positions
E3 ligase RAD18 targets phosphorylated IRF3 to terminate <i>IFNB1</i> transcription
Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02256-x IRF3 initiates type I IFN transcription, and this is required for host defense. Here, Chen and colleagues show that RAD18 terminates the transcriptional activity of Read More
