T cells engineered to target a shared β-catenin mutation eradicate solid tumors in mice Summary Genetically engineered T cells targeting a specific mutation in the β-catenin protein have shown remarkable success in eradicating solid tumors Read More
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Education, Research & Positions
TCR-engineered T cells targeting a shared β-catenin mutation eradicate solid
Nature Immunology, Published online: 27 August 2025; doi:10.1038/s41590-025-02252-1 TCR-T cells are T cells engineered to express a specific T cell receptor. Here the authors present a TCR-T cell that targets CTNNB1-S37F, Read More
Science, Volume 389, Issue 6762, Page 778-779, August 2025. Summary Without knowing the specific articles or content within that issue of Science, I can only provide a general summary. Science, Volume 389, Issue 6762, published in August 2025, likely contains cutting-edge Read More
Education, Research & Positions
Proteogenomic approach to immunopeptidomics of ovarian tumors identifies shared peptide
Proteogenomic approach to immunopeptidomics of ovarian tumors identifies shared peptide vaccine candidates Summary A proteogenomic approach was used to analyze ovarian tumors, combining genomic and proteomic data with immunopeptidomics to identify potential shared peptide vaccine Read More
The world’s greatest concentration of ancestral human remains, in South Africa, poses a 2-million-year-old riddle of coexistence Summary South Africa holds the world’s largest collection of ancestral human remains, presenting a profound mystery: Read More
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