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Tags :receptors

Targeting the roots of myeloid malignancies with T cell receptors

Dr AF Saeed Dr AF Saeed 21st August 2025

Targeting the roots of myeloid malignancies with T cell receptors Summary Targeting myeloid malignancies, like leukemia, remains challenging due to disease heterogeneity and relapse risks. A promising approach focuses on using T cell receptors (TCRs) Read More

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Chemosensor receptors are lipid-detecting regulators of macrophage function in cancer

Dr AF Saeed Dr AF Saeed 1st July 2025

Nature Immunology, Published online: 30 June 2025; doi:10.1038/s41590-025-02191-x Tumor-associated macrophages are pivotal in control over solid tumors. Here the authors show that these macrophages express chemosensors that detect lipid variants in the tumor Read More