Immunotherapies have made significant strides in treating advanced cancers, a feat that was once considered impossible. These treatments, with their Summary Immunotherapies represent a major breakthrough in cancer treatment, particularly for advanced stages previously Read More
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TIGIT in cancer: from mechanism of action to promising immunotherapeutic
TIGIT in cancer: from mechanism of action to promising immunotherapeutic strategies Summary TIGIT (T-cell immunoreceptor with Ig and ITIM domains) is an inhibitory receptor on T and NK cells that dampens anti-tumor immunity. It competes Read More
Two-dimensional (2D) materials, thin crystalline substances only a few atoms thick, have numerous advantageous properties compared to their three-dimensional (3D) bulk counterparts. Most notably, many of these materials allow electricity to flow through them more Read More
A vaccine successfully induced specific B cells in rhesus macaques, paving the way for an effective HIV vaccine in humans. Summary A promising HIV vaccine strategy has shown success in rhesus macaques. The vaccine effectively Read More
Immune-checkpoint targeting drug conjugates: a novel class of promising therapeutic
Immune-checkpoint targeting drug conjugates: a novel class of promising therapeutic agents for cancer treatment Summary Immune-checkpoint targeting drug conjugates (ICT-DCs) represent a promising new strategy in cancer treatment. These conjugates combine the precision of immune Read More