ICANS and mortality after CAR-T therapy for NHL patients can be predicted using physical function measures of falls, balance and strength deficits, and use of an assistive device Summary Physical function assessments can predict mortality Read More
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Education, Research & Positions
Downregulation of MICA/MICB improves cell persistence and clinical activity of
Downregulation of MICA/MICB improves cell persistence and clinical activity of NKG2DL CAR T-cells in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic neoplasia Summary CAR T-cell therapy targeting NKG2D ligands (Read More
Education, Research & Positions
Efficacy and safety of induction immunotherapy plus chemotherapy in patients
Efficacy and safety of induction immunotherapy plus chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a meta-analysis Summary This meta-analysis investigates the efficacy and safety of adding induction immunotherapy to chemotherapy for locoregionally advanced nasopharyngeal Read More
Education, Research & Positions
Study Reveals New Insights into Immune Dysregulation in Patients with
Chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) is a sustained illness (6-months or more) where the patient has persistent fatigue with worseni Summary Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (ME/CFS) is a debilitating, long-term illness Read More
Education, Research & Positions
Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for
Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1 Summary This research investigates the potential of CAR-T cell therapy to treat malignant peripheral nerve Read More
Education, Research & Positions
Novel Antibody Response Improves Immunotherapy in Cancer Patients – New
Cancer treatment has progressed over the last century. Specifically, the advent of immunotherapy has revolutionized how physicians treat patients. The goal Summary Cancer treatment has dramatically evolved, particularly with the rise of immunotherapy. Immunotherapy aims Read More
GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system Summary GD2 ganglioside, highly expressed in several pediatric central nervous system (CNS) tumors like neuroblastoma and medulloblastoma, presents Read More
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Treatment Given Before and After Surgery Improves Survival in Patients
Cancer is a broad term used to describe the uncontrollable proliferation of mutated cells deleterious to the body. Any tissue in the body can become mutate Summary Cancer is a term for diseases where abnormal Read More
A UCSF study reveals that aging may actually ease lupus symptoms. Immune overactivity in mid-life appears to diminish in older patients, reversing the usual age-related rise in inflammation and suggesting new treatment strategies. Lupus: An Read More
Education, Research & Positions
Autoantibody spark response predicts treatment outcome in patients receiving chemoradiation
Autoantibody spark response predicts treatment outcome in patients receiving chemoradiation followed by durvalumab therapy Summary A study revealed that the development of new autoantibodies, termed “autoantibody spark,” following chemoradiation therapy (CRT) predicts the effectiveness of Read More
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