Exploring the metabolic-immune score in advanced NSCLC treated with immunotherapy Summary This research investigates the relationship between a “metabolic-immune score” and outcomes in advanced Non-Small Cell Lung Cancer (NSCLC) patients treated with immunotherapy. The score Read More
First-line sacituzumab tirumotecan with tagitanlimab in advanced non-small-cell lung cancer: a phase 2 trial Summary A phase 2 trial investigated sacituzumab tirumotecan combined with tagitanlimab as a first-line treatment for advanced non-small-cell lung cancer (NSCLC). The study Read More
Investigating the correlation between IDO1/PD-L1 expression or co-expression and EGFR/KRAS gene mutations in advanced NSCLC Summary This study explores the relationship between IDO1 and PD-L1 expression (both individually and together) and the presence Read More
OH2 oncolytic virus inhibits non-small-cell lung cancer metastasis via β-catenin pathway suppression Summary Oncolytic virus OH2 effectively inhibits non-small-cell lung cancer (NSCLC) metastasis. Researchers demonstrated that OH2 suppresses the Wnt/β-catenin signaling pathway, a key Read More
Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13 + T and CXCL9+ cells after radiotherapy combined with anti-PD-L1 therapy Summary A study using single-cell spatial analysis with the Xenium platform investigated the effects of Read More
Tumor aneuploidy as a prognostic and predictive biomarker in immune checkpoint blockade Summary Tumor aneuploidy, an abnormal chromosome number, is increasingly recognized as a crucial factor influencing cancer progression and response to immunotherapy, particularly immune Read More
Neoadjuvant nivolumab plus chemotherapy improves overall survival in resectable NSCLC Summary Neoadjuvant nivolumab combined with chemotherapy significantly improves overall survival (OS) in patients with resectable non-small cell lung cancer (NSCLC) compared to chemotherapy alone. This Read More
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