Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02273-w Humanized mice for MS studies Summary A new study in Nature Immunology (August 29, 2025) highlights the development of humanized mice for studying Multiple Sclerosis (MS). The Read More
Tags :Neuroimmunology
Education, Research & Positions
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy – New
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy Summary Cancer-induced nerve damage can foster resistance to anti-PD-1 immunotherapy. Specifically, nerves damaged by the tumor release neuropeptides that suppress immune cell activity, particularly T cell function. Read More
Nature Immunology, Published online: 18 August 2025; doi:10.1038/s41590-025-02230-7 Latz et al. review the molecular mechanisms that drive NLRP3 inflammasome activation and regulation, and discuss emerging targeting strategies. Summary In a review published in Read More
Education, Research & Positions
CGRP-related neuropeptide adrenomedullin 2 promotes tissue-protective ILC2 responses and limits
Nature Immunology, Published online: 15 August 2025; doi:10.1038/s41590-025-02243-2 Artis and colleagues show that enteric neurons produce CGRP-related ADM2 to promote intestinal tissue-protective functions in ILC2s. Summary A new study in Nature Immunology Read More
Nature Immunology, Published online: 11 August 2025; doi:10.1038/s41590-025-02237-0 CD4+ T cells migrate from the gut and adipose tissue to the brain parenchyma, in mouse and human, transmitting information on diet and microbiome to Read More
Nature Immunology, Published online: 24 July 2025; doi:10.1038/s41590-025-02205-8 Single-cell spatial proteomics paired with chromatin accessibility mapping identifies a diverse range of human microglial immune states. In Alzheimer’s disease, hippocampal microglia tend to Read More
Education, Research & Positions
Spatial proteomics of Alzheimer’s disease-specific human microglial states – New
Nature Immunology, Published online: 22 July 2025; doi:10.1038/s41590-025-02203-w In this Resource paper, the authors use MIBI spatial proteomics to map microglial cell states in brains from cognitively normal humans and those with Alzheimer’Read More
Nature Immunology, Published online: 30 June 2025; doi:10.1038/s41590-025-02216-5 Neurons protect against fibrosis Summary New research published in Nature Immunology reveals a surprising role for neurons in preventing fibrosis. The study demonstrates that neurons, Read More
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