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Tags :Metabolism
MiR-93 promotes fatty liver disease, but vitamin B3 can counteract its effects. This discovery suggests a new treatment approach. Roughly 30% of people worldwide are affected by metabolic-associated fatty liver disease (MASLD), a condition that until Read More
Researchers have discovered that brain cancer cells reprogram their sugar metabolism, a vulnerability that can be exploited in mice to impede tumor growth and enhance therapeutic outcomes. Glioblastomas are the most aggressive type of malignant Read More
Education, Research & Positions
Ultra-Processed Foods Add Fat Without Extra Calories and Disrupt Hormones
Ultra-processed foods don’t just pack on pounds — they change the body in hidden ways. In a tightly controlled study, young men gained more fat mass on a processed diet even when calorie counts were Read More
Education, Research & Positions
Cornell Scientists Unlock the Secret to Age-Defying Weight Control –
Scientists at Cornell have uncovered a way to potentially reverse age-related weight gain by reactivating a special type of fat called beige fat. Unlike ordinary white fat that stores calories, beige fat burns energy like Read More
Glucose drives T cell signaling. Stronger signals mean better cancer defense. For the body’s disease-fighting T cells, glucose is much more than just a simple sugar rush. Scientists at the Van Andel Institute have Read More
Gut microbes produce D-lactate that worsens metabolism. A trap for it restores healthier blood sugar and liver function. A group of Canadian researchers has identified an unexpected way to lower blood sugar and protect the Read More
Education, Research & Positions
Targeting MondoA–TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment –
Targeting MondoA–TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment Summary Cancer cells often produce high levels of lactic acid, creating an immunosuppressive microenvironment. This study investigates targeting the MondoA-TXNIP pathway in this lactic acid-rich Read More
Education, Research & Positions
Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer
Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer Summary Pancreatic cancer often resists immunotherapy, and this resistance is linked to elevated levels of spermine, a polyamine involved in cell growth and survival. Researchers Read More
SARDH in the 1-C metabolism sculpts the T-cell fate and serves as a potential cancer therapeutic target Summary SARAH (Sarcosine Dehydrogenase) plays a crucial role in 1-carbon (1-C) metabolism, a pathway vital for cell growth Read More
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