Engineering B cells to treat and study human disease Summary Engineering B cells, the antibody-producing cells of the immune system, offers powerful tools for both treating and studying human diseases. Genetically modified B cells can Read More
Tags :immunotherapy
Education, Research & Positions
Real-world study of first-line immunotherapy combined with chemoradiotherapy in esophageal
Real-world study of first-line immunotherapy combined with chemoradiotherapy in esophageal squamous cell carcinoma Summary A real-world study investigated the efficacy of first-line immunotherapy (likely PD-1/PD-L1 inhibitors) combined with chemoradiotherapy (CRT) in patients with esophageal Read More
Education, Research & Positions
Chimeric exosomes-derived immunomodulator restoring lymph nodes microenvironment for sensitizing TNBC
Chimeric exosomes-derived immunomodulator restoring lymph nodes microenvironment for sensitizing TNBC immunotherapy Summary This research explores a novel approach to improve immunotherapy response in Triple-Negative Breast Cancer (TNBC) using chimeric exosomes. These engineered exosomes, derived from Read More
Education, Research & Positions
Caerin 1.1/1.9 interfere KHDRBS1-DDX5 regulatory axis to induce IL-18 mediated
Caerin 1.1/1.9 interfere KHDRBS1-DDX5 regulatory axis to induce IL-18 mediated pyroptosis in a HeLa cell tumour model Summary Caerin 1.1 and 1.9, peptides, disrupt the KHDRBS1-DDX5 regulatory axis in HeLa cancer cells. This disruption triggers IL-18 Read More
Education, Research & Positions
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation Summary Massively parallel immunopeptidome sequencing (MPIS) uses DNA sequencing to identify peptides presented by MHC molecules on cell surfaces, offering a comprehensive view Read More
Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy Summary CRISPR-Cas9 technology can enhance CAR T-cell immunotherapy by improving T-cell function and targeting specificity. This study focuses on a streamlined manufacturing process for Read More
Education, Research & Positions
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade Summary This research presents a novel CD27 agonistic antibody engineered for enhanced activity. By promoting hexamerization (Read More
Education, Research & Positions
The untapped potential of radiation and immunotherapy for hormone receptor-positive
The untapped potential of radiation and immunotherapy for hormone receptor-positive breast cancer Summary Hormone receptor-positive (HR+) breast cancer, while treatable, often develops resistance to endocrine therapy. Emerging research explores combining radiation therapy with immunotherapy to Read More
ICANS risk model in CD19 CAR-T therapy: insights from serum and CSF cytokine profiling Summary This study explores the predictive power of the Immune Cell-Associated Neurotoxicity Syndrome (ICANS) risk model in CD19 CAR-T therapy patients Read More
Humoral determinants of checkpoint immunotherapy Summary Humoral factors, like antibodies and complement proteins, play a crucial but often overlooked role in checkpoint immunotherapy efficacy. Beyond T-cell activation, checkpoint inhibitors can influence antibody-dependent cellular cytotoxicity (ADCC) Read More
Site Logo
Powered by AI
New Journal Citation Reports (JCR) 2025
All-Time Views
1 Million+ Views and Counting..!
Follow me on Linkedin for Latest Jobs and Scholarships
Subscribe Youtube
Celebrating 7 Years
It has been 7 years since it was launched in late July 2018, and it is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
Site Trust Score
Google Safe
