Science, Volume 389, Issue 6760, Page 571-572, August 2025. Summary I cannot provide a summary without the actual content of the Science article (Volume 389, Issue 6760, Page 571-572, August 2025). My knowledge is based on data up to my last Read More
Tags :immunotherapy
Education, Research & Positions
Advanced Ovarian and Endometrial Cancers Respond to Combination Immunotherapy –
Gynecological clear cell cancers (CCCs), very aggressive forms of ovarian and endometrial malignancies, respond poorly to chemotherapy. The low respo Summary Gynecological clear cell cancers (CCCs) are aggressive cancers of the ovary and endometrium Read More
For many cases of gastric (stomach) or gastroesophageal (GEJ) cancer, the standard treatment involves surgical removal of the malignant tissue, along with Summary Surgical removal is a cornerstone of treatment for many gastric and gastroesophageal (Read More
Education, Research & Positions
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target Summary This study used a comprehensive “multi-omics” approach (combining genomics, proteomics, etc.) to understand the T-cell environment Read More
Education, Research & Positions
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation Summary ULBP2 CAR-T cells show promise in improving gastric cancer immunotherapy by targeting and killing tumor cells and simultaneously disrupting the tumor microenvironment. The Read More
Education, Research & Positions
Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis
Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis Summary Sorafenib, a multi-kinase inhibitor, enhances the anti-tumor activity of Th9 cells (a type of T helper cell) in lung metastasis models. Specifically, sorafenib treatment Read More
A novel chimeric antigen receptor T-cell therapy targeting CD84 for the treatment of acute myeloid and T-cell lymphoblastic leukemias Summary A novel CAR-T cell therapy targeting CD84 is showing promise for treating acute myeloid leukemia (Read More
The gut microbiota in cancer immunity and immunotherapy Summary The gut microbiota plays a crucial role in shaping both local and systemic immune responses, significantly impacting cancer development and response to immunotherapy. Specific bacterial species Read More
Surprising role of CMV in shaping outcomes of immunotherapy for melanoma — chronic infection yields favourable survival Summary Cytomegalovirus (CMV), a common chronic virus, surprisingly improves immunotherapy outcomes in melanoma patients. Research suggests that individuals with Read More
Education, Research & Positions
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function Summary This study investigates the relationship between the functional avidity of anti-B7H3 CAR-T cells and the antigen density required Read More
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