Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a phase 2 trial Summary This phase 2 trial explores a novel approach to overcome resistance to anti-PD-1 immunotherapy in triple-negative breast cancer (TNBC). Researchers aim to Read More
Multiscale dynamic immunomodulation by a nanoemulsified Trojan-TLR7/8 adjuvant for robust protection against heterologous pandemic and endemic viruses Summary A novel nanoemulsion adjuvant, encapsulating a TLR7/8 agonist, was developed for enhanced and broad-spectrum antiviral immunity. This “Read More
The rapidly evolving paradigm of neoadjuvant immunotherapy across cancer types Summary Neoadjuvant immunotherapy (NAIT), administering immunotherapy before surgery, is rapidly changing cancer treatment. Early trials show promising results, including higher rates of pathological complete response (Read More
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