Nature Reviews Immunology, Published online: 16 June 2025; doi:10.1038/s41577-025-01193-y Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate Read More
Tags :Immune
Education, Research & Positions
Hypoimmunogenic HLA-E Single Chain Inhibits Alloreactive Immune Responses
Abstract Chimeric Ag receptor T cells derived from universal donors are susceptible to recipient immunologic rejection, which may limit their in vivo persistence and compromise treatment efficacy. In this study, we generated HLA class I–Read More
Education, Research & Positions
Innate immune responses to pathogens at the maternal–fetal interface
Nature Reviews Immunology, Published online: 18 June 2025; doi:10.1038/s41577-025-01191-0 During pregnancy, innate immune mechanisms at the maternal–fetal interface are important for protecting the developing fetus from pathogens. However, excessive immune activation can Read More
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