London School of Economics and Political Science – Secretary’s Division<br />Salary: £43,277 to £51,714 per annum inclusive with potential to progress to £55,497 pa inclusive of London allowance Read more… Credits: jobs.ac.uk DisclaimerRead More
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Trinity College Dublin, The University of Dublin<br />Salary: €72,339 to €81,177 per annum Read more… Credits: jobs.ac.uk DisclaimerRead More
Nature Immunology, Published online: 16 September 2025; doi:10.1038/s41590-025-02284-7 CD4+ T follicular helper (TFH) cells that develop in response to a range of pathogens share aspects of a common gene signature. However, cytokine environments, Read More
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in
Promoting the therapeutic potential of interleukin-7 (IL-7) by expression in viral vectors Summary Viral vectors offer a promising avenue for delivering interleukin-7 (IL-7), a cytokine crucial for T cell survival and proliferation, to harness its Read More
Microbiota-mediated mechanisms of mucosal immunity across the lifespan – New
Nature Immunology, Published online: 16 September 2025; doi:10.1038/s41590-025-02281-w Here Iliev et al. review the interactions between the microbiota and the mucosal immune system from infancy to adulthood, highlighting the impact on health and Read More
Downregulation of MICA/MICB improves cell persistence and clinical activity of
Downregulation of MICA/MICB improves cell persistence and clinical activity of NKG2DL CAR T-cells in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic neoplasia Summary CAR T-cell therapy targeting NKG2D ligands (Read More
A spatial map of MAPK-activated immunosuppressive myeloid populations in pediatric
Nature Immunology, Published online: 15 September 2025; doi:10.1038/s41590-025-02268-7 Here the authors spatially map human pediatric low-grade gliomas using imaging mass cytometry, focusing on immunosuppressive myeloid cell populations and their functionality in tumor–immune Read More
Delaying pyroptosis with an AI-screened gasdermin D pore blocker mitigates
Nature Immunology, Published online: 15 September 2025; doi:10.1038/s41590-025-02280-x Wang and colleagues show that an AI-assisted designed peptide obstructs GSDMD pores and inhibits IL-1β and IL-18 release and pyroptosis. Summary A study published in Read More
Lymph nodes fuel KLF2-dependent effector CD8<sup>+</sup> T cell differentiation during
Nature Immunology, Published online: 15 September 2025; doi:10.1038/s41590-025-02276-7 Here the authors show a function for lymph nodes in the maintenance of effector T cell differentiation and function during chronic infection and checkpoint blockade, Read More
Antigen-specific Treg cells induce infectious tolerance Summary Antigen-specific regulatory T cells (Tregs) can induce “infectious tolerance,” a powerful mechanism where Tregs not only suppress immune responses against a specific antigen but also convert other immune Read More







