The findings challenge long-standing assumptions about therapy-related cancers. They also highlight how drug actions can substitute for genetic changes in tumor development. An international team of researchers, including Prof. Kirsten Kübler from the Berlin Read More
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Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer Summary Engineering natural killer (NK) cells with chimeric antigen receptors (CARs) targeting tumor-associated antigens Read More
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The anti-Kronos effect: How bacterial viruses protect their offspring to
University of Toronto researchers have uncovered how bacterial viruses protect their progeny in order to maximize their reach. The phenomenon, described in a study published in Nature, relies on viral proteins to fine-tune structures on Read More
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Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis
Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis Summary Sorafenib, a multi-kinase inhibitor, enhances the anti-tumor activity of Th9 cells (a type of T helper cell) in lung metastasis models. Specifically, sorafenib treatment Read More
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Anti-cancer effect of interleukin-2 fused to flagellin expressed by tumor-targeting
Anti-cancer effect of interleukin-2 fused to flagellin expressed by tumor-targeting Salmonella Summary Researchers explored a novel cancer therapy using tumor-targeting Salmonella bacteria. They engineered the bacteria to express a fusion protein combining interleukin-2 (IL-2), an Read More
Women and older adults using semaglutide, a popular anti-obesity medication, may face a heightened risk of muscle loss. A recent study suggests that women and older adults who use the weight-loss drug semaglutide could be Read More
The generation of electricity from heat, also known as thermoelectric energy conversion, has proved to be advantageous for various real-world applications. For instance, it proved useful for the generation of energy during space expeditions and Read More
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