Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities Summary CRISPR base and prime editing offer promising avenues for enhancing T cell immunotherapies by precisely modifying the T cell genome. Read More
EchoBack-CAR T cells: a sonogenetic solution to the persistent challenges of solid tumor immunotherapy Summary EchoBack-CAR T cells offer a novel approach to solid tumor immunotherapy by addressing key limitations of traditional CAR T-cell therapies. Read More
Researchers analyzed human breast milk samples and uncovered gene expression patterns tied to high and low breast milk supply. Summary A recent study analyzing human breast milk has identified specific gene expression patterns associated with Read More
A discovery in Uzbekistan shows that the roots of farming stretched far beyond the Fertile Crescent. The emergence of agriculture during the Neolithic marked a turning point in the development of human culture. While scholars Read More
A study led by Jenny Frediani at Stockholm University has revealed a planet-forming disk with a strikingly unusual chemical composition: an unexpectedly high abundance of carbon dioxide (CO2) in regions where Earth-like planets may one Read More
The dawn of agriculture in the Neolithic was a major development in the evolution of modern human culture. Although scientists agree that farming developed independently several times around the world, including in Africa, the Americas, Read More
GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system Summary GD2 ganglioside, highly expressed in several pediatric central nervous system (CNS) tumors like neuroblastoma and medulloblastoma, presents Read More
The study reveals that many young people in Africa, and some in the U.S., may have a non-autoimmune form of type 1 diabetes, suggesting the potential for more accurate diagnoses and targeted treatments. A major Read More
Researchers taking the first-ever direct measurement of atom temperature in extremely hot materials inadvertently disproved a decades-old theory and upended our understanding of superheating. Summary Scientists, for the first time, directly measured atom temperature within Read More
The method has applications in organic chemistry, particularly within the pharmaceutical industry. A team of scientists has developed an electrochemical technique that enables precise, para-position single-carbon insertion into polysubstituted pyrroles. This advancement holds significant promise Read More
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