Cellular immunity Archives

T<sub>FH</sub> cell programs by pathogen and species – New Study

Dr AF Saeed Dr AF Saeed 16th September 2025

Nature Immunology, Published online: 16 September 2025; doi:10.1038/s41590-025-02284-7 CD4+ T follicular helper (TFH) cells that develop in response to a range of pathogens share aspects of a common gene signature. However, cytokine environments, Read More

Education, Research & Positions

Six degrees of TGFβ – New Study

Dr AF Saeed Dr AF Saeed 29th July 2025

Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02201-y TGFβ-mediated signals enable CD8+ T cells to establish tissue-residence. IL-4 and PD-1 are each connected to TGFβ signaling to regulate the formation of CD8+ Read More

Education, Research & Positions

Transcription factors TCF4 and KLF4 respectively control the development of

Dr AF Saeed Dr AF Saeed 23rd July 2025

Nature Immunology, Published online: 23 July 2025; doi:10.1038/s41590-025-02208-5 Here Zhu et al. investigate the ontogeny of type 2 dendritic cells (DC2s) in mice. Using Klf4 expression to distinguish conventional DC precursors from plasmacytoid Read More