Research on rare post-mortem brain tissue shows changes in gene activity, offering new insight into the biological basis of depression. Researchers from McGill University and the Douglas Institute have discovered two distinct types of brain Read More
Tags :Cells
Nature Immunology, Published online: 22 September 2025; doi:10.1038/s41590-025-02285-6 The authors spatially and functionally map innate lymphoid cells in the human female genital tract at homeostasis, uncovering tissue-specific and subset-specific distribution and functions, and Read More
In a fruit fly, nerve cells that detect limb movement are silenced when the insect walks or grooms. This on-off switch may help the nervous system to shift between two states: one helps keep the Read More
Education, Research & Positions
Epigenetic imprinting in innate lymphoid cell precursors directs the lineage
Nature Immunology, Published online: 18 September 2025; doi:10.1038/s41590-025-02261-0 Wang and colleagues show that specific DNA methylation profiles mark the ILC progenitors (ILCP) that would differentiate into ILC1, ILC2 or ILC3 subsets. Summary Wang Read More
Education, Research & Positions
EchoBack-CAR T cells: a sonogenetic solution to the persistent challenges
EchoBack-CAR T cells: a sonogenetic solution to the persistent challenges of solid tumor immunotherapy Summary EchoBack-CAR T cells offer a novel approach to solid tumor immunotherapy by addressing key limitations of traditional CAR T-cell therapies. Read More
Japanese researchers have created a dynamic microfluidic channel that greatly enhances the performance of flow cytometers. Flow cytometry has enabled many breakthroughs in medicine and drug discovery. The technique examines single cells by detecting the Read More
Pressure from surrounding tissues activates invasive programs in cancer cells. This mechanical stress rewires epigenetic regulation. Cancer cells are notoriously adaptable, capable of shifting their characteristics as they spread throughout the body. Many of these Read More
Scientists at Gladstone Institutes uncovered a surprising reason why dopamine-producing neurons, crucial for smooth body movements, die in Parkinson’s disease. In mice, when these neurons were kept overactive for weeks, they began to falter, Read More
Antigen-specific Treg cells induce infectious tolerance Summary Antigen-specific regulatory T cells (Tregs) can induce “infectious tolerance,” a powerful mechanism where Tregs not only suppress immune responses against a specific antigen but also convert other immune Read More
Education, Research & Positions
Damage-induced IL-18 stimulates thymic NK cells limiting endogenous tissue regeneration
Nature Immunology, Published online: 11 September 2025; doi:10.1038/s41590-025-02270-z The thymus is sensitive to acute insults including infection, as well as to injury from chemotherapy and myeloablative conditioning before hematopoietic cell transplantation. Here, Granadier Read More
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