Commensals join the effector game – Immunology Research

296Immunology


Nature Immunology, Published online: 24 March 2026; doi:10.1038/s41590-026-02467-w

Bacterial type III secretion systems, traditionally viewed as virulence factors, are prevalent in healthy gut microbiomes, where they deliver effectors that modulate human immune signaling and influence susceptibility to inflammatory diseases.



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