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      Tuft cells feel the pain – Immunology Research

      296Immunology
      Tuft cells feel the pain – Immunology Research


      Nature Immunology, Published online: 10 February 2026; doi:10.1038/s41590-026-02440-7

      Type 2 immunity in the gut is regulated by an interplay between epithelial and immune cells. A recent Nature paper shows that pain receptors amplify this response by promoting the differentiation of epithelial tuft cells.



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