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      Better and closer glycan-independent anti-V3 antibodies to help HIV-1 vaccine – Immunology Research

      296Immunology


      Nature Immunology, Published online: 03 February 2026; doi:10.1038/s41590-025-02409-y

      The identification of a new Asn332 glycan-independent anti-HIV-1 neutralizing antibody that targets the V3 epitope, together with an Asn332 glycan-deficient priming immunogen capable of inducing B cell precursors of Asn332 glycan-dependent and -independent neutralizing antibodies, redefines the V3 loop in HIV-1 vaccine development.



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