This review provides a comprehensive overview of the intestinal crypt and its diverse cell types, highlighting their roles in nutrient absorption, mucus production, antimicrobial defense, and GLP-1-regulated metabolism. It also positions the gut as a powerful model of epithelial self-renewal and stem cell biology, with organoid systems further yielding new insights into cell division and plasticity during regeneration.
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Shifting paradigms in tissue stem cell biology: Insights from the intestine – Research
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