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      EcDNA-borne structural variants drive oncogenic fusion transcript amplification – Research

      Education, Research & Positions
      EcDNA-borne structural variants drive oncogenic fusion transcript amplification – Research



      Extrachromosomal DNA (ecDNA) is a major source of oncogenic fusions across cancer types, generating tissue-specific fusion landscapes with diagnostic potential. EcDNA-borne PVT1 5′-end fusions stabilize partner RNAs and boost oncogene output.



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      Textbooks Challenged: Scientists Discover New Mechanism of Cell Division – Science News

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      Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all forms of life, but scientists have long...
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