The establishment of the intravital imaging of externally immobilized embryos (IMEE) method enables stable, high-resolution imaging of mouse embryos to investigate cellular dynamics in the developing mouse brain, including neuronal migration patterns, neurons’ dynamic interactions with vasculature and microglia, and microglial surveillance behaviors under physiological conditions and environmental stress.
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Intravital observation of neuronal and immune cell dynamics in the developing mammalian brain – Research
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