Björn Högberg explains how his team engineered a DNA origami nanorobot that activates only in tumors to trigger cancer cell death.



Summary

Björn Högberg’s team has developed a DNA origami nanorobot designed to target and destroy cancer cells. This innovative approach uses DNA to construct a tiny robot that remains inactive until it encounters a specific tumor microenvironment. Upon recognition, the nanorobot opens, exposing a “payload” that triggers cell death selectively within the tumor. This targeted activation minimizes off-target effects and maximizes the therapeutic impact directly at the cancerous tissue, offering a promising new strategy for cancer treatment.

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