Experimental Drug Reverses PTSD Symptoms in Mice – Already in Human Trials – New Study/Science Updates
Excessive levels of GABA released by astrocytes impair the brain’s ability to extinguish fear responses in PTSD, but a newly identified drug target offers promising hope for treatment. Many people with post-traumatic stress disorder (PTSD) continue to relive painful memories long after the actual threat is gone. Their brains seem unable to let go of […]
Summary
In PTSD, individuals struggle to extinguish fear responses, reliving traumatic memories long after the event. Recent research suggests excessive GABA release by astrocytes hinders this fear extinction process. This overabundance of GABA impairs the brain’s natural ability to learn that the threat is no longer present. The discovery of a specific drug target related to this GABA release offers a potential new avenue for developing effective PTSD treatments, holding promise for helping patients overcome persistent fear and anxiety.
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