Neanderthals and Denisovans passed along gene that provides a sticky shield against germs



Summary

A gene variant, OAS1, inherited from Neanderthals and Denisovans, fortifies human cells against viral infections. This gene boosts the production of an enzyme that acts like a “sticky shield,” disrupting viral RNA and hindering replication. Researchers believe this inherited defense provided a significant survival advantage as early humans migrated into Eurasia, encountering novel pathogens. This discovery highlights the tangible legacy of archaic hominins in our immune systems, offering protection against modern viruses.

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