A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with fewer off-target effects.



Summary

A novel AI tool predicts how alterations in peptides affect T cell receptor (TCR) binding, crucial for immunotherapy design. This model allows researchers to understand and predict how different peptide sequences interact with TCRs, enabling the creation of immunotherapies that are more specific and less likely to trigger unintended immune responses. By accurately simulating these interactions, the tool facilitates the development of safer and more effective treatments by minimizing off-target effects.

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