Radioligand therapy is a revolutionary approach in modern cancer treatment that uses engineered molecules to deliver targeted radiation directly to cancer cells. By attaching radioactive isotopes to specific molecules that recognize tumor markers, this precision medicine technique allows focused destruction of cancer cells while minimizing damage to surrounding healthy tissues. Bacteriophages, viruses that naturally infect bacteria, are now being modified as innovative delivery vehicles for these radioactive therapeutic agents. Their unique properties including biocompatibility, precise genetic engineering capabilities, and ability to carry targeting ligands make them excellent nanocarriers for precision oncology applications.
✅ Position Type: PhD Position (4 years)
✅ Institution: The Belgian Nuclear Research Centre (SCK CEN)
✅ Location: Mol, Belgium
✅ Research Focus: Development of modular bacteriophage-based nanocarriers for targeted radioligand therapy (RLT) in cancer treatment
✅ Duration: 4 years (Estimated)
✅ Starting Date: October 1, 2026
✅ Application Deadline: March 31, 2026 at 12:00 (Europe/Brussels time)
✅ Salary: Not specified in the posting
✅ Contract Type: Full-time, Temporary
✅ Hours Per Week: 40🎯 Required Qualifications:
✅ Master of Sciences or Master of Sciences in Engineering
✅ Background in: Bio-engineering, Biology, or Biochemistry
✅ Excellent English language skills📝 Research Description:
This groundbreaking PhD project focuses on developing modular bacteriophage-based nanocarriers for targeted radioligand therapy to treat cancer. The research will combine modern genetic engineering, chemical bioconjugation, and radiochemistry techniques to create programmable carriers that can deliver radiotherapeutic payloads directly to tumor cells. By integrating tumor-targeting ligands, radiometal chelators, and bio-orthogonal functional groups, engineered phages will be transformed into precision medicine tools that can selectively damage tumor DNA while minimizing off-target toxicity. The four-year project will progress from molecular design through preclinical validation in tumor models, contributing significantly to advancing nuclear cancer therapies.🎯 Benefits of SCK CEN PhD Program:
✅ Academic and Research-Oriented: Close cooperation with the academic sector combined with a unique international research environment
✅ World-Class Facilities: Access to innovative facilities specifically designed for nuclear experiments
✅ Expert Mentorship: Work alongside supportive experienced experts in the field
✅ Multidisciplinary Research: Integration with diverse areas of expertise and knowledge exchange opportunities
✅ Excellent Training: Access to SCK CEN Academy’s renowned internal training courses and professional development📧 Step-by-Step Application Guide:
1️⃣ Visit the official application website: https://www.sckcen.be/en/thesis-and-internship-topics/modular-phage-based-nanocarriers-radioligand-therapy-5634
2️⃣ Review the detailed project description and ensure you meet all eligibility criteria
3️⃣ Prepare your application documents (specific requirements available on the SCK CEN PhD application page)
4️⃣ Review the selection process details at: https://www.sckcen.be/en/sck-cen-academy/phds-postdocs/phd-theses#anchor-apply
5️⃣ Submit your complete application before the deadline: March 31, 2026 at 12:00 (Europe/Brussels time)
6️⃣ For questions, contact: academy@sckcen.be🔗 Application Link:
https://www.sckcen.be/en/thesis-and-internship-topics/modular-phage-based-nanocarriers-radioligand-therapy-5634
📧 Contact Email: academy@sckcen.be
🌐 EURAXESS Posting: https://euraxess.ec.europa.eu/jobs/398328
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