Immunologists at UNIGE have revealed a previously unknown anti-tumor role of CD4 T lymphocytes, marking a breakthrough that could pave the way for a new generation of immunotherapies. Cancer treatments that harness the body’s own immune system, known as immunotherapy, are advancing rapidly. Most current therapies focus on CD8 T lymphocytes, also known as “killer […]



Summary

UNIGE immunologists have discovered a novel anti-tumor function of CD4 T lymphocytes, challenging the focus on CD8 T cells in current immunotherapies. Their research reveals that specific CD4 T cell subsets can directly kill tumor cells, offering a new avenue for cancer treatment. This groundbreaking finding could lead to the development of a new generation of immunotherapies that utilize and enhance the tumor-fighting capabilities of CD4 T cells. The discovery expands our understanding of the immune system’s potential to combat cancer.

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