Efficacy and safety of immunosuppressive therapy versus cyclosporine combined with avatrombopag in older adults with severe aplastic anemia: a multicenter prospective study



Summary

A multicenter prospective study investigated the efficacy and safety of immunosuppressive therapy (IST) alone versus IST combined with avatrombopag in older adults with severe aplastic anemia (SAA). The study compared treatment response rates, hematological recovery, and adverse events between the two groups. Findings aimed to determine if adding avatrombopag to standard IST improved outcomes for older SAA patients who often experience lower response rates and increased toxicity with traditional therapies. Ultimately, the research sought to refine treatment strategies for this vulnerable population, enhancing efficacy and reducing treatment-related complications.

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