Code: 6013/2020/10

The main task of the research group Mechanisms of Propagation is to elucidate underlying mechanisms in disease propagation and spreading in neurodegenerative diseases with a main focus on Amyothrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD) and Parkinson’s disease (PD). Using innovative animal models and patient samples we try to understand how and why protein aggregates are transmitted from cell to cell. We also explore transmission to non-neuronal cells and try to pinpoint the contribution of peripheral inflammation. Furthermore, epigenetic profiling of different cell populations or single cells allows us to discover new pathways involved in ALS, PD and FTD and identify new therapeutic targets.


Your tasks

  • Management and support the analysis of large-scale genomics and proteomics data sets
  • Interpretation of large scale sequencing data
  • Advice of experimental design for ideal data output
  • Development of user-friendly tools for data analysis and tracking of experiments
  • Prepare and write manuscripts for publication in international scientific journals
  • Oral presentation of results on local, national, and international conferences
  • Interface between scientists working in the lab and informatical analysis

Requirements

  • PhD degree in bioinformatics, physics, computer science, biochemistry, or a related field.
  • Technical knowledge on the field of genomics and proteomics, and its implications on data analysis are ideal
  • Experience in using classical statistical methods and ideally also new modern concepts
  • Strong programming skills in scripting languages like R, Matlab or Python, knowledge of Java or in designing and querying databases is a plus
  • A keen interest in neurodegenerative diseases and a profound knowledge in neuroscience
  • English language is a prerequisite
  • We are looking for candidates who are open-minded, creative team-player, enthusiastic, have strong analytical skills, think critically, and with good social skills

We offer

  • Working in an international team within a stimulating research environment and with very well equipped laboratories
  • An international environment characterized by a strong focus on science and research
  • A high potential for the individual development of our employees
  • Targeted personnel development
  • 2 years with the possibility of prolongation
  • Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD Bund)

Application files: CV, Motivation letter, Bachelor and Master qualifications, Reference letters, Certificates

Apply:

https://jobs.dzne.de/en/jobs/50640/apply

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