The Institute of Biomaterials and Biomolecular Systems,
Research Unit Molecular and Synthetic Plant Virology,
offers in the course of an interdisciplinary project
as soon as possible a
Postdoc position (f/m/d)
(Molecular Biology/Biochemistry/Natural Sciences; E13 TV-L)
(for a period of three years).
Within the DFG-funded collaborative Project ‘Virus-on-a-chip: Integration of plant virus particles with electronic chips for a label-free biosensing (ViroChip)’, our Research Unit Molecular and Synthetic Plant Virology (Prof. Dr. Christina Wege, apl.) investigates methods for an externally controlled self-assembly of novel RNA-protein bionanoparticles from tobacco mosaic virus (TMV) building blocks, their use as carriers for various sensor enzymes including product analyses, and immobilization strategies on technical supports. The partner lab for Chemical Sensors and Biosensors at the Institute of Nano- and Biotechnologies (INB), Aachen University of Applied Sciences (Prof. Dr.-Ing. Michael Schöning), integrates the enzyme-equipped TMV derivatives in field-effect biosensors, in order to improve and characterize their performance and to develop theoretical models of sensor functioning. Long-term goal are universal design rules for constructing a new class of advantageous biosensors for a wide variety of analytes, as tested for a set of relevant target compounds in the course of the project.
Tasks and perspectives: The project offers opportunities for the creative development of literature-deduced novel strategies to exploit biological self-assembly in the fabrication of technically attractive, ‘smart’ biofunctional materials. New concepts for the design of different enzyme-based ‘real-world’ point-of-care sensors may be established collaboratively. Some work packages can be accomplished by help of jointly supervised B.Sc. and M.Sc. theses, which may enable the publication of intermediate results and an in-depth workout of further ideas. To this end, excellent communication and writing skills in English are important, and fluent German language advantageous. The project management and planning experience gained throughout the work is expected to prepare for careers in both research institutions and companies. Our contributions will be fully equipped lab and technical facilities, strong international contacts and an inspiring, pleasant working environment.
Major methods: Molecular biology and biochemical/biophysical methods for isolating plant viruses, protein expression and purification, cloning, in vitro transcription, RNA and DNA preparation, modification and analytics, conjugation chemistry, enzyme characterization, light and electron microscopy techniques, some in direct collaboration with/at the INB.
Further information may be provided by Prof. Dr. Christina Wege (apl.): [email protected]; see also https://www.bio.uni-stuttgart.de/en/institute/team/Wege/ and https://www.bio.uni-stuttgart.de/en/molbio/ .
Application: Please submit your complete electronic application (subject: ‘ViroChip’; file name: ‘Surname_First Name-ViroChip.pdf’) until 06 January 2021 as a single PDF file, including contact data for two referees, to Prof. Dr. Christina Wege, University of Stuttgart, Institute of Biomaterials and Biomolecular Systems, Research Unit Molecular and Synthetic Plant Virology, via e-mail: .
Contact data and homepages:
University of Stuttgart
Institute of Biomaterials and Biomolecular Systems
Molecular and Synthetic Plant Virology
Prof. Dr. Christina Wege (apl.)
T +49 711 685 65073
on how the University protects personal data in accordance with Article 13 of the GDPR can be found under the following link: https://www.uni-stuttgart.de/en/privacy-notice/job-application/
The University of Stuttgart is an equal opportunity employer. Applications from women are strongly encouraged. Severely challenged persons will be given preference in case of equal qualifications.
Your qualifications: M.Sc. or German Diplom degree in Natural or Life Sciences, PhD/Dr. rer. nat. degree in Biology, Biochemistry or similar with convincing result; strong and profound knowledge of molecular biology and biochemistry, basic skills in bioinformatics and biophysics, in-depth practical experience in various molecular biology methods; the ability to work accurately, independently, and reliably in a well-organized manner; excellent communication skills, team spirit and work ethics; high motivation and enthusiasm for intense interdisciplinary collaborative work, direct interaction with students and scientific discussions. Previous relevant experience is a benefit.
Art der Beschäftigung Vollzeit Zeitraum der Beschäftigung as soon as possible for a period of three years Vergütung E13 TV-L Bewerbungs-
Hochschule / Einrichtung Universität Stuttgart Institut / Einrichtung Institut für Biomaterialien und biomolekulare Systeme; Molekulare und Synthetische Pflanzenvirologie Standort 70569 Stuttgart, Deutschland KontaktpersonFrau apl. Prof. Dr. Christina Wege Telefon +4971168565073